This article is for informational purposes only. It does not claim that CBD cures or treats cancer. We’re sharing current research and recent findings to help readers better understand the topic.
Quick overview:
- We provide a broad overview of current research on CBD oil and cancer.
- We review the latest research findings.
- We explore possible mechanisms researchers have studied in relation to CBD and cancer.
- We address important considerations related to CBD use and share expert opinions.
CBD oil has drawn attention in research, but evidence about its role in cancer is still limited. In this article, we look at what current studies say about CBD and cancer.
Early Research Questions About CBD and Cancer
Research into CBD and cancer has been ongoing for decades. Early studies sparked interest, but human evidence is still limited, and CBD should not be presented as a cancer treatment.
What Does the Evidence Say About CBD in Cancer Research?
A 2019 review examined CBD research in cell and animal models. It found that results varied by cancer type and dose, and more human research is needed.
What Research Says About CBD and Breast Cancer
- A 2010 preclinical study explored CBD in breast cancer models and reported effects on cell-growth pathways. These findings are preliminary and do not prove clinical benefit.
- A 2011 study examined CBD in tumor-cell models and reported effects on cell-death pathways. These findings are preliminary and do not establish a cancer treatment.
CBD Oil and Cancer Research: Still Under Investigation
- A 2019 review looked at cannabinoids in pancreatic cancer models. It found early preclinical findings, but there are not yet enough human clinical trials to draw conclusions about effectiveness.
- A 2014 preclinical study looked at CBD in colon cancer models. Because this was not human research, more studies are needed.
These early findings may help guide future research into cannabis-based medicines, but they do not establish a treatment for cancer.

CBD Oil and Cancer Research: What the Research Says
What CBD Oil and Cannabis Oil Are, and Where They Come From
CBD oil, also called cannabis oil, contains cannabidiol, a natural compound extracted from hemp (Cannabis sativa). Unlike THC, CBD is non-intoxicating, so it does not produce a high. During production, the CBD extract from the hemp plant is blended with carrier oils and adjusted to the desired concentration.
Cannabis Oil and Cancer Research: What Does the Science Say?
Cancer treatments can have side effects, and researchers are still studying cannabinoids, including CBD, in this area.
Research on CBD and cancer is ongoing. Next, we review current findings to see what researchers are studying.
Research into CBD and cancer-related mechanisms
Current status of clinical trials
Currently, there are only a limited number of clinical trials on CBD. Here are some key points:
- Several Phase I and Phase II studies are ongoing
- They mainly focus on symptom management.
- Few large-scale, randomized controlled trials are underway
|
Trial Phase |
Focus |
Status |
|
Phase I |
Safety |
Ongoing |
|
Phase II |
Effectiveness |
Early stage |
|
Phase III |
Comparative |
In planning |
Findings from animal studies
In animal studies, researchers have seen early findings in the following areas:
- Mouse Study Findings
- What Rat Studies Examined
- Research has explored programmed cell death (apoptosis) in a range of cancer cell types.
These animal study results are early, and more research is needed before moving further into human trials.
What Cell Studies Found
Lab studies on cell cultures offer early insights into how CBD may work:
- Preclinical Studies on Cancer Cells
- Researchers also study angiogenesis, or the formation of new blood vessels, in cancer research.
- Researchers are still studying oxidative stress.
These early findings are limited, and more research is needed to understand the mechanisms involved.
Research limitations and challenges
Research on CBD and cancer is still limited and faces many challenges today.
- Important Considerations
- Legal Considerations
- Research Funding Challenges
- Standardization Challenges
These factors significantly impact the progress and quality of research.

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CBD Oil and Cancer Research: What We Know So Far
Research on CBD and cancer is still limited. Some studies are exploring possible effects in cancer care, but it is too early to make clear claims about benefits.
Managing Discomfort
Some research has explored CBD for pain, but the evidence is still developing. A 2020 review looked at animal and clinical studies and found the overall picture was still incomplete.
Quality-of-Life Findings in Research
Some people look to CBD for general wellness, but research on its effects in cancer care is still limited. It should not be presented as a way to improve energy or sleep in cancer patients.
CBD Oil During Chemotherapy: What Researchers Are Studying
Research is still limited, and CBD should not be positioned as a way to manage chemotherapy side effects. Researchers continue to study several areas:
|
Possible Side Effects and Safety Considerations |
Potential effects of CBD oil |
|
Digestive Upset |
Results Are Mixed, and More Research Is Needed |
|
Loss of appetite |
Some studies have examined appetite and weight changes. |
|
Fatigue |
Effects Can Vary From Person to Person |
|
Possible Nervous System Effects |
Early Research on Brain and Nervous System Effects |
Coping With Emotional Strain During Cancer Care
A cancer diagnosis can be overwhelming, and many patients experience emotional stress during treatment. Research on CBD and mood is still limited, so it should not be presented as a treatment for anxiety or depression.
While research is still preliminary, anyone considering CBD during cancer treatment should talk with a healthcare professional. Next, we look at key factors to keep in mind.
Things to Consider Before Using CBD Oil
CBD oil is often discussed in cancer research, but there are several important factors to keep in mind. Let’s take a closer look at what should be considered.
CBD Oil and Possible Drug Interactions
CBD may interact with some medications, especially those processed by the liver. This can change how a medicine works or raise the risk of side effects.
|
Medication type |
Possible Drug Interaction |
|
Blood thinners |
Increased risk of bleeding |
|
Anti-seizure medications |
Why results can vary |
|
Chemotherapy drugs |
Altered metabolism |
Possible side effects of CBD
CBD may cause side effects in some people, including:
- Fatigue
- Appetite Changes
- Diarrhea
- Dry mouth
CBD Dosing and How It’s Used
CBD dosing can vary by person and product. A common approach is to start with a low amount and increase gradually if needed, ideally with guidance from a healthcare professional. CBD products can be used in several ways:
- CBD oil drops taken under the tongue
- CBD creams or balms applied to the skin
=>Click here for more detailed information about CBD oil dosing.
What is CBD?
All the important information in one place!
CBD Oil and Cancer: What Oncologists Generally Say
Although oncologists continue to discuss CBD oil, they generally advise caution and emphasize that:
- More human studies are needed
- CBD oil cannot replace conventional treatments
- Talk to your doctor before using CBD
If someone is considering CBD during cancer treatment, they should talk with their healthcare team first. A clinician can help review possible interactions and safety considerations.
Summary
Research on CBD and cancer is still evolving. More studies are needed to understand potential effects and safety in people.
CBD oil is not a substitute for cancer treatment. If you’re considering it while receiving treatment, talk with a healthcare professional first.
The studies and research details cited in this article are available through the embedded links in the Sources section below.
References and Scientific Sources- Barbara Dariš, Mojca Tancer Verboten, Željko Knez, Polonca Ferk (2019): Cannabinoids in cancer treatment: Therapeutic potential and legislation
- Emily S. Seltzer, Andrea K. Watters, Danny MacKenzie, Jr., Lauren M. Granat, and Dong Zhang (2020): Cannabidiol (CBD)) research review
- Sean D. McAllister, Ryuichi Murase, Rigel T. Christian, Darryl Lau, Anne J. Zielinski, Juanita Allison, Carolina Almanza, Arash Pakdel, Jasmine Lee, Chandani Limbad, Yong Liu, Robert J. Debs, Dan H. Moore & Pierre-Yves Desprez (2010): Cannabidiol research article
- Ashutosh Shrivastava, Paula M. Kuzontkoski, Jerome E. Groopman, Anil Prasad (2011): Cannabidiol research on apoptosis and autophagy
- Golnaz Sharafi, Hong He, Mehrdad Nikfarjam (2019): Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer
- Barbara Romano, Francesca Borrelli, Ester Pagano, Maria Grazia Cascio, Roger G. Pertwee, Angelo A. Izzo (2014): Inhibition of colon carcinogenesis by a standardized Cannabis sativa extract with high content of cannabidiol
- Reference: Brigitta Kis, Feng Chen Ifrim, Valentina Buda, Stefana Avram, Ioana Zinuca Pavel, Diana Antal, Virgil Paunescu, Cristina Adriana Dehelean, Florina Ardelean, Zorita Diaconeasa, Codruta Soica, Corina Danciu (2019): Cannabidiol – from Plant to Human Body: A Promising Bioactive Molecule with Multi-Target Effects in Cancer
- Lia Costa, Cristina Amaral , Natércia Teixeira, Georgina Correia-da-Silva, Bruno M Fonseca (2015): Cannabinoid-induced autophagy: Protective or death role? DOI: 10.1016/j.prostaglandins.2015.12.006
- Scott Shannon, Nicole Lewis, Heather Lee, and Shannon Hughes (2019): Cannabidiol in Anxiety and Sleep: A Large Case Series
- Jakub Mlost, Marta Bryk, Katarzyna Starowicz (2020): Cannabidiol for Pain Treatment: Focus on Pharmacology and Mechanism of Action
