{"id":3796,"date":"2021-07-22T12:36:22","date_gmt":"2021-07-22T10:36:22","guid":{"rendered":"https:\/\/usamedical.com\/sk\/?p=3796"},"modified":"2021-07-22T12:36:22","modified_gmt":"2021-07-22T10:36:22","slug":"cbg","status":"publish","type":"post","link":"https:\/\/usamedical.com\/sk\/cbg\/","title":{"rendered":"\u010co je CBG a ako sa l\u00ed\u0161i od CBD?"},"content":{"rendered":"\t\t
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Kanabigerol alebo CBG<\/b> je kanabinoid, teda jedna z mnoh\u00fdch zl\u00fa\u010den\u00edn nach\u00e1dzaj\u00facich sa v rastline konope. Najzn\u00e1mej\u0161\u00edmi kanabinoidmi s\u00fa <\/span>kanabidiol (CBD)<\/span><\/a> a <\/span>tetrahydrokanabinol (THC)<\/span><\/a>, no v poslednej dobe z\u00edskava na popularite aj <\/span>CBG<\/b>, ktor\u00e9mu sa pripisuj\u00fa viacer\u00e9 s\u013eubn\u00e9 pozit\u00edvne <\/span>\u00fa\u010dinky<\/span>.<\/span><\/p>

Pozrime sa na s\u00fa\u010dasn\u00fd stav v\u00fdskumov zameran\u00fdch na CBG a porovnajme <\/span>\u00fa\u010dinky CBD<\/span><\/a> a CBG.\u00a0<\/span><\/p>

\u00a0<\/h2>

\u010co je to CBG?<\/strong><\/h2>

CBG je podobne ako CBD druh kanabonoidu, ktor\u00fd sa prirodzene nach\u00e1dza v rastline konope. CBG je v\u00fdchodiskovou l\u00e1tkou (<\/span>prekurzor<\/span><\/a>) pre ostatn\u00e9 kanabinoidy, ktor\u00e9 z CBG v raslitne vznikaj\u00fa. CBGA alebo kyselina kanabigerolov\u00e1, je forma CBG z ktorej v rastline vznik\u00e1 CBD, THC a CBC (kanabichrom\u00e9n). C<\/span>BG m\u00e1 preto podobn\u00e9 \u00fa\u010dinky ako CBD a pod\u013ea v\u00fdskumov m\u00f4\u017ee ovplyvni\u0165 aj n\u00e1\u0161 endokanabinoidn\u00fd syst\u00e9m.<\/span><\/p>

\u00a0<\/span><\/p>

Spoznajte potenci\u00e1lne \u00fa\u010dinky CBG, \u201ematky\u201c v\u0161etk\u00fdch kanabinoidov<\/b><\/h3>

Na za\u010diatok treba poznamena\u0165, \u017ee <\/span>doposia\u013e nem\u00e1me dostatok v\u00fdskumov oh\u013eadom \u00fa\u010dinkov CBG na \u013eu\u010foch,<\/b> preto\u017ee v\u00e4\u010d\u0161ina <\/span>\u0161t\u00fadi\u00ed bola roben\u00e1 na zvierat\u00e1ch<\/span><\/a>. Napr\u00edklad na z\u00e1klade \u0161t\u00fadie z roku 2020 m\u00f4\u017eeme predpoklada\u0165, \u017ee CBG m\u00e1 v\u00fdznamn\u00e9 <\/span>antibakteri\u00e1lne \u00fa\u010dinky. <\/b>Tie sa prejavili najm\u00e4 pri multirezistentnom zlatom stafylokokovi. Okrem toho m\u00f4\u017eeme na z\u00e1klade doteraz vykonan\u00fdch \u0161t\u00fadi\u00ed predpoklada\u0165 aj \u010fal\u0161ie \u00fa\u010dinky, ktor\u00e9 popisujeme na najbli\u017e\u0161\u00edch riadkoch.<\/span><\/p>

\u00a0<\/span><\/p>

CBG m\u00e1 pravdepodobne protiz\u00e1palov\u00e9 \u00fa\u010dinky<\/b><\/h3>

Protiz\u00e1palov\u00e9 \u00fa\u010dinky sa preuk\u00e1zali najm\u00e4 <\/span>v pr\u00edpade z\u00e1palov\u00fdch ochoren\u00ed \u010driev, <\/b>ako je napr\u00edklad Cronova choroba \u010di ulcer\u00f3zna kolit\u00edda. <\/span>V\u00fdskum Biochemical Pharmacology z roku 2013 uk\u00e1zal<\/span><\/a>, \u017ee CBG redukuje produkciu oxidu dusnat\u00e9ho a reakt\u00edvneho kysl\u00edka v \u010drev\u00e1ch, \u010d\u00edm zni\u017euje niektor\u00e9 nepr\u00edjemn\u00e9 pr\u00edznaky t\u00fdchto ochoren\u00ed.<\/span><\/p>

\u00a0<\/span><\/p>

CBG m\u00f4\u017ee pom\u00e1ha\u0165 stimulova\u0165 chu\u0165 do jedla<\/b><\/h3>

University of Reading zverejnila v roku 2016 \u0161t\u00fadiu<\/span><\/a>, pod\u013ea ktorej<\/span> CBG napom\u00e1ha zvy\u0161ova\u0165 chu\u0165 do jedla. <\/b>Hlodavce, na ktor\u00fdch bol \u0161t\u00fadia roben\u00e1, dvojn\u00e1sobne nav\u00fd\u0161ili svoj jed\u00e1lni\u010dek. Z tohto d\u00f4vodu sa odhaduje, \u017ee by CBG mohlo pom\u00f4c\u0165 aj \u017een\u00e1m trpiacim anorexiou, bul\u00edmiou a \u010fal\u0161\u00edmi poruchami potravy, ktor\u00e9 s\u00fa sprev\u00e1dzan\u00e9 aj depresiami \u010di \u00fazkos\u0165ami.<\/span><\/p>

\u00a0<\/span><\/p>

CBG ako pomocn\u00edk pri lie\u010dbe zelen\u00e9ho z\u00e1kalu<\/b><\/h3>

Pod\u013ea \u0161t\u00fadii British Journal of Ophthalmology<\/span><\/a> CBG zlep\u0161uje odtok tekut\u00edn z oka,<\/b> \u010d\u00edm zni\u017euje vn\u00fatroo\u010dn\u00fd tlak a zlep\u0161uje krvn\u00fd obeh oka. V\u010faka tomu sa dostane do oka viac krvi bohat\u0161ej na kysl\u00edk, \u010do m\u00f4\u017ee pom\u00e1ha\u0165 v lie\u010dbe o\u010dn\u00fdch ochoren\u00ed, napr\u00edklad aj zelen\u00e9ho z\u00e1kalu.<\/span><\/p>

\u00a0<\/span><\/p>

CBG m\u00f4\u017ee pom\u00e1ha\u0165 potl\u00e1\u010da\u0165 boles\u0165<\/b><\/h3>

Pod\u013ea \u0161t\u00fadie v Biological and Pharmaceutical Bulletin m\u00e1 CBG podobn\u00e9 <\/span>analgetick\u00e9 vlastnosti<\/b><\/a> ako Ibalgin a \u010fal\u0161ie nesteroidn\u00e9 protiz\u00e1palov\u00e9 lieky proti bolesti. Dokonca by mal by\u0165 \u00fa\u010dinnej\u0161\u00ed na boles\u0165 ne\u017e THC.<\/span><\/p>

\u00a0<\/span><\/p>

CBG m\u00f4\u017ee pom\u00f4c\u0165 aj v oblasti ment\u00e1lneho zdravia<\/b><\/h3>

CBG pravdepodobne dok\u00e1\u017ee <\/span>navodi\u0165 stav uvo\u013enenia a relax\u00e1cie<\/b><\/a>, <\/b>a to v\u010faka vplyvu na anandam\u00edn, tzv. horm\u00f3n bla\u017eenosti, a v\u010faka nepriamemu vplyvu na zv\u00fd\u0161enie seroton\u00ednu, horm\u00f3nu \u0161\u0165astia. Z t\u00fdchto d\u00f4vodov sa \u010dasto hovor\u00ed o doposia\u013e nepresk\u00famanom potenci\u00e1li CBG v terapi\u00e1ch proti \u00fazkosti, nespavosti \u010di depresii, aj ke\u010f by v \u017eiadnom pr\u00edpade nemal nahr\u00e1dza\u0165 odborn\u00fa psychiatrick\u00fa pomoc.<\/span><\/p>

\u00a0<\/span><\/p>

Ako u\u017e\u00edva\u0165 CBG<\/b><\/h3>

Sp\u00f4sob u\u017e\u00edvania CBG je podobn\u00fd ako sp\u00f4sob konzum\u00e1cie CBD. Naj\u010dastej\u0161ie sa m\u00f4\u017eete stretn\u00fa\u0165 s <\/span>produktami CBG vo forme kvapiek v kombin\u00e1cii s konopn\u00fdm olejom. <\/b>V tomto pr\u00edpade v\u00e1m posta\u010d\u00ed nakvapka\u0165 si t\u00fato zmes pod jazyk. V pr\u00edpade prid\u00e1vania CBG do jedla sa nemus\u00edte ob\u00e1va\u0165 miernej tepelnej \u00fapravy, t\u00e1to na vlastnosti CBG toti\u017e nevpl\u00fdva.<\/span><\/p>

\u00a0<\/span><\/p>

Potenci\u00e1lne rizik\u00e1 u\u017e\u00edvania CBG<\/b><\/h3>

Z doposia\u013e uskuto\u010dnen\u00fdch \u0161t\u00fadi\u00ed <\/span>zatia\u013e nevypl\u00fdvaj\u00fa \u017eiadne v\u00e1\u017ene ved\u013eaj\u0161ie \u00fa\u010dinky u\u017e\u00edvania CBG<\/b> a aj tie menej v\u00e1\u017ene s\u00fa vz\u00e1cne. Ka\u017edop\u00e1dne v\u0161ak odborn\u00edci odpor\u00fa\u010daj\u00fa konzultova\u0165 jeho u\u017e\u00edvanie s lek\u00e1rom, a to najm\u00e4 v pr\u00edpade, ak u\u017e\u00edvate antibiotik\u00e1, kortikoidy, lieky na srdce a cholesterol \u010di antihistaminik\u00e1. Av\u0161ak to, \u017ee by mohlo CBD metabolizmus t\u00fdchto liekov ovplyvni\u0165 je zatia\u013e kv\u00f4li nedostato\u010dn\u00fdm v\u00fdskumom iba domnienkou.<\/span><\/p>

\u00a0<\/div>

Ako sa vyr\u00e1ba CBG<\/strong><\/h3>

CBG sa z\u00edskava z mlad\u00fdch rastl\u00edn konope, preto\u017ee obsahuj\u00fa vy\u0161\u0161ie mno\u017estv\u00e1 CBG ako plne vyvinut\u00e9 rastliny.\u00a0<\/span><\/p>

\u00daplne zrel\u00e9 rastliny s vysokou koncentr\u00e1ciou THC (25 – 30 % ) a CBD (20 -25 %)\u00a0 maj\u00fa v\u00fdrazne ni\u017e\u0161iu koncentr\u00e1ciu CBG (len zhruba 1%), preto\u017ee v\u00e4\u010d\u0161ina kanabigerolu sa u\u017e po\u010das rastu konope (marihuany) premenila na CBD a THC.<\/span><\/p>

Kv\u00f4li tomu s\u00fa CBG v\u00fdrobky vz\u00e1cnej\u0161ie a <\/span>drah\u0161ie<\/span><\/a> ako napr. <\/span>CBD olej<\/span><\/a>.\u00a0<\/span><\/p>

Niektor\u00e9 odrody konope (White CBG, Super Glue CBG a Jack Frost CBG) maj\u00fa vy\u0161\u0161\u00ed obsah CBG, perto sa kultivuj\u00fa na v\u00fdrobu CBG produktov.\u00a0<\/span><\/p>

CBG sa vyr\u00e1ba podobne ako CBD a to superkritickou extrakciou CO2<\/span><\/a>.\u00a0<\/span><\/p>

\u00a0<\/h2>

Ak\u00fd je rozdiel medzi CBG a CBD olejom?<\/strong><\/h2>

CBG sa \u010dasto porovn\u00e1va s CBD, preto\u017ee pod\u013ea v\u00fdskumov tieto dve zl\u00fa\u010deniny s\u00fa si v mnohom podobn\u00e9 a obe p\u00f4sobia na <\/span>endokanabinoidn\u00fd syst\u00e9m<\/span><\/a>. CBG ani CBD nie s\u00fa psychoakt\u00edvne, t. j. nemenia stav vedomia ako to je v pr\u00edpade THC.\u00a0<\/span><\/p>

Jedn\u00fdm z prv\u00fdch rozdielov medzi nimi je, \u017ee konope vo v\u00e4\u010d\u0161ine pr\u00edpadov obsahuje iba 1 % kanabigerolu, a obsah CBD je a\u017e 25 %. Kv\u00f4li n\u00e1ro\u010dnej\u0161ej v\u00fdrobe v\u00fdrobcovia uprednost\u0148uj\u00fa v\u00fdrobu CBD oleja pred CBG.<\/span><\/p>

\u00a0<\/h3>

CBG sa l\u00ed\u0161i od CBD nieko\u013ek\u00fdmi d\u00f4le\u017eit\u00fdmi faktormi:<\/strong><\/h3>

\u00a0<\/h4>

Molekul\u00e1rna \u0161trukt\u00fara\u00a0<\/b><\/h4>

Kanabigerol (CBG) a kanabidiol (CBD) maj\u00fa r\u00f4zne molekul\u00e1rne \u0161trukt\u00fary, teda usporiadanie at\u00f3mov vod\u00edka, uhl\u00edka a kysl\u00edka, ktor\u00e9 tvoria priestorov\u00e9 usporiadanie biologicky akt\u00edvnych l\u00e1tok a tie potom zapadaj\u00fa do receptorov n\u00e1\u0161ho tela ako <\/span>z\u00e1mok a k\u013e\u00fa\u010d<\/b>. Na tomto princ\u00edpe ur\u010dit\u00e9 l\u00e1tky\/ lieky ovplyv\u0148uj\u00fa len ur\u010dit\u00e9 org\u00e1ny, syst\u00e9my tela = <\/span>interakcia liekov v tele<\/a>.<\/p>

CBD a CBG maj\u00fa r\u00f4zne priestorov\u00e9 usporiadania (3D tvar) a preto sa via\u017eu na kanabinoidn\u00e9 receptory (receptory CB1 a CB2) r\u00f4znymi sp\u00f4sobmi = maj\u00fa aj r\u00f4zne \u00fa\u010dinky na telo.\u00a0<\/span><\/p>

Farmakol\u00f3gia<\/b><\/a><\/h4>

Pod\u013ea v\u00fdskumov CBD a CBG sa v tele spr\u00e1vaj\u00fa inak (aktivuj\u00fa in\u00e9 receptory v tele) a interaguj\u00fa s na\u0161\u00edm telom. Preto sa \u00fa\u010dinky CBD a CBG m\u00f4\u017eu l\u00ed\u0161i\u0165.\u00a0<\/span><\/p>

Chu\u0165 do jedla\u00a0<\/b><\/h4>

CBG sa l\u00ed\u0161i od CBD aj t\u00fdm ako stimuluje chu\u0165 do jedla. V\u00fdskum na potkanoch uk\u00e1zal, \u017ee d\u00e1vky CBG povzbudzovali zvierat\u00e1 k tomu, aby jedli viac ako dvojn\u00e1sobok ich be\u017en\u00e9ho pr\u00edjmu potravy. V inej \u0161t\u00fadii kanabidiol (CBD) v\u00fdznamne zn\u00ed\u017eil celkov\u00fd pr\u00edjem potravy a chu\u0165 do jedla.<\/span><\/p>

\ud83d\udd2c Zdroj:\u00a0<\/span><\/p>

Cannabinol and cannabidiol exert opposing effects on rat feeding patterns<\/span><\/a><\/p>

Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats<\/span><\/a><\/p>

\u00a0<\/h2>

Nev\u00fdhody CBG<\/strong><\/h2>

CBG sa v rastlin\u00e1ch konope nach\u00e1dza v men\u0161om mno\u017estve ako in\u00e9 kanabinoidy. V\u00e4\u010d\u0161ina odr\u00f4d obsahuje len 1 % kanabigerolu (CBG) v porovnan\u00ed s 20-25 % CBD alebo 25-30 % THC. To je d\u00f4vod, pre\u010do s\u00fa v\u00fdrobky s obsahom CBG na trhu \u010dasto drah\u00e9. Vzh\u013eadom na \u0165a\u017ekosti s dod\u00e1vkami experimentuj\u00fa pestovatelia konopy s kontinu\u00e1lnym kr\u00ed\u017een\u00edm, pr\u00edpadne genetickou manipul\u00e1ciou, aby rastliny produkovali viac kanabigerolu.<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\"V\u00fdskum\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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\u00da\u010dinky a potenci\u00e1lne mo\u017enosti vyu\u017eitia CBG<\/strong><\/h2>

Aj ke\u010f v s\u00fa\u010dasnosti neexistuj\u00fa \u017eiadne klinick\u00e9 \u0161t\u00fadie, ktor\u00e9 by potvrdzovali \u00fa\u010dinky CBG na \u010dloveka, mno\u017estvo predklinick\u00fdch \u0161t\u00fadi\u00ed ukazuje a mno\u017estvo pozit\u00edvnych potenci\u00e1lnych terapeutick\u00fdch \u00fa\u010dinkoch CBG na organizmus. Samozrejme je potrebn\u00fdch viac pokusov na \u013eu\u010foch.<\/span><\/p>

Dobrou spr\u00e1vou je, \u017ee v\u00e4\u010d\u0161inu v\u00fdhod CBG mo\u017eno z\u00edska\u0165 aj konzum\u00e1ciou \u0161irokospektr\u00e1lnych CBD olejov, ktor\u00e9 obsahuj\u00fa v\u0161etky kanabinoidy nach\u00e1dzaj\u00face sa v konope, vr\u00e1tane mal\u00e9ho mno\u017estva kanabigerolu, ale bez \u0161kodliv\u00fdch \u00fa\u010dinkov THC. Kanabinoidy pou\u017e\u00edvan\u00e9 spolo\u010dne m\u00f4\u017eu takto vz\u00e1jomne zvy\u0161ova\u0165 svoju \u00fa\u010dinnos\u0165 (po anglicky: <\/span>entourage effect<\/span><\/a>).<\/span><\/p>

\ud83d\udca1\u00a0Pre viac inform\u00e1ci\u00ed o CBD olejoch kliknite sem<\/a><\/strong><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

Kanabigerol alebo CBG je kanabinoid, teda jedna z mnoh\u00fdch zl\u00fa\u010den\u00edn nach\u00e1dzaj\u00facich sa v rastline konope. Najzn\u00e1mej\u0161\u00edmi kanabinoidmi s\u00fa kanabidiol (CBD) a tetrahydrokanabinol (THC), no v poslednej dobe z\u00edskava na popularite aj CBG, ktor\u00e9mu sa pripisuj\u00fa viacer\u00e9 s\u013eubn\u00e9 pozit\u00edvne \u00fa\u010dinky. Pozrime sa na s\u00fa\u010dasn\u00fd stav v\u00fdskumov zameran\u00fdch na CBG a porovnajme \u00fa\u010dinky CBD a CBG.    […]<\/p>\n","protected":false},"author":4,"featured_media":3800,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[51,52],"tags":[],"class_list":["post-3796","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cbd-informacie","category-ok"],"acf":[],"yoast_head":"\n\u010co je CBG a ako sa l\u00ed\u0161i od CBD? - USAmedical.sk<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/usamedical.com\/sk\/cbg\/\" \/>\n<meta property=\"og:locale\" content=\"sk_SK\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u010co je CBG a ako sa l\u00ed\u0161i od CBD? - USAmedical.sk\" \/>\n<meta property=\"og:description\" content=\"Kanabigerol alebo CBG je kanabinoid, teda jedna z mnoh\u00fdch zl\u00fa\u010den\u00edn nach\u00e1dzaj\u00facich sa v rastline konope. Najzn\u00e1mej\u0161\u00edmi kanabinoidmi s\u00fa kanabidiol (CBD) a tetrahydrokanabinol (THC), no v poslednej dobe z\u00edskava na popularite aj CBG, ktor\u00e9mu sa pripisuj\u00fa viacer\u00e9 s\u013eubn\u00e9 pozit\u00edvne \u00fa\u010dinky. 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